Severe Sepsis and Septic Shock: Management Bundle

Identifying Attributes

Care Settings
Rural and Remote Care
Country
United States of America
Publishing Organisation
National Quality Forum
Type of Quality Indicator
Structure
IOM Quality Dimension
Safety
Domain
Adverse Events

Defining Attributes

Definition
Numerator

Patients who received ALL of the following:

Within three hours of presentation of severe sepsis:

• Initial lactate level measurement

• Broad spectrum or other antibiotics administered

• Blood cultures drawn prior to antibiotics

AND received within six hours of presentation of severe sepsis. ONLY if the initial lactate is elevated:

• Repeat lactate level measurement

AND within three hours of initial hypotension:

• Resuscitation with 30 mL/kg crystalloid fluids

OR within three hours of septic shock:

• Resuscitation with 30 mL/kg crystalloid fluids

AND within six hours of septic shock presentation, ONLY if hypotension persists after fluid administration:

• Vasopressors are administered

AND within six hours of septic shock presentation, if hypotension persists after fluid administration or initial lactate >= 4 mmol/L:

• Repeat volume status and tissue perfusion assessment is performed

Denominator

Inpatients age 18 and over with an ICD-10-CM Principal or Other Diagnosis Code of Sepsis, Severe Sepsis, or Septic Shock and not equal to U07.1 (COVID-19).

Exclusions

The following patients are excluded from the denominator:

• Patients with an ICD-10-CM Principal or Other Diagnosis Code of U07.1 (COVID-19)

• Directive for Comfort Care or Palliative Care within six hours of presentation of severe sepsis

• Directive for Comfort Care or Palliative Care within six hours of presentation of septic shock

• Administrative contraindication to care within six hours of presentation of severe sepsis

• Administrative contraindication to care within six hours of presentation of septic shock

• Length of Stay >120 days

• Transfer in from another acute care facility

• Patients enrolled in a clinical trial for sepsis, severe sepsis or septic shock treatment or intervention

• Patients with severe sepsis who are discharged within six hours of presentation

• Patients with septic shock who are discharged within six hours of presentation

• Patients receiving IV antibiotics for more than 24 hours prior to presentation of severe sepsis

Use of Risk Adjustment
No
Risk Adjustments

None

Stratifications

None

Collection and Reporting Attributes

Type of Data Collection
Electronic/paper chart records
Data Collection Methods

Electronic Health Data, Paper Patient Medical Records

Frequency of Data Collection
Frequency of Data Collection in Days
Reporting Methods
Reporting Frequency
Reporting Frequency in Days
Indicator Has Recommended Targets
No

Source and Reference Attributes

Evidence Source

National Quality Forum 2022 Key Rural Measures: An Update List of Measures to Advance Rural Health Priorities, Draft 1, page 1-26

Link to Measurement Tools
Quality Indicator Confirmed to be Part of a Program Used to Monitor Quality and Safety of Care Among Older People at a Population-Level between 2012-2022
No
Assessed by the Australian Consortium for Aged Care Collaborators as Generally Containing Good Properties (Importance and Scientific Acceptability)
No
Australian Consortium for Aged Care Endorsed
No
Identified by PHARMA-Care Project
No
Upload Date
02 December 2025